Pancreatic cancer (PC) is the third leading cause of cancer-related deaths in the United States (US). Nationally and in the state of Florida, PC incidence and mortality rates in African Americans (AA) are 50% to 90% higher than rates in Non-Hispanic Whites (NHW) and other racial groups. Reasons for these disparities remain unexplained and underexplored. The purpose of this research is to create a state-wide biobank to conduct basic, clinical, population-based, and translational pancreatic cancer health disparities research. Secondary goals include utilization of the biobank to test the central hypothesis that cancer cachexia may underlie racial disparities in PC. A biobank is a valuable resource that involves collection, processing, and storage of blood, other bodily fluids, and tissue (obtained during biopsy or surgery) to improve the investigator's understanding of health and disease. When combined with information and medical images obtained through routine care, the investigators will be able to investigate biological processes that may underlie differences and poor outcomes and target them with more effective therapeutic strategies tailored to the individual.